The Effect of a Ketogenic Diet (vs a Carbohydrate-Based Diet), on Cognitive Performance, Mood and Subjective Sleepiness during 36 Hours of Extended Wakefulness

Détails

Catégorie : Ketogenic Diet / Healthy diet

Publication : lundi 5 décembre 2022 15:02

The Effect of a 2-Week Ketogenic Diet, versus a Carbohydrate-Based Diet, on Cognitive Performance, Mood and Subjective Sleepiness during 36 Hours of Extended Wakefulness in Military Personnel

The KD appeared to improve cognitive performance, mood and sleepiness during 36 h of extended wakefulness compared with the CHO-based diet. This suggests the KD could be considered for military operations when sleep deprivation is anticipated.

Abstract Open Access

https://www.mdpi.com/2673-9992/9/1/22

https://mdpi-res.com/d_attachment/msf/msf-09-00022/article_deploy/msf-09-00022-with-cover.pdf?version=1669410918

Metabolic characteristics of keto-adapted ultra-endurance runners

Détails

Catégorie : Ketogenic Diet / Healthy diet

Publication : mardi 29 juin 2021 06:21

In summary, these results provide the first documentation of the metabolic adaptations associated with long-term con- sumption of a very low-carbohydrate/high-fat diet in highly trained keto-adapted ultra-endurance athletes. The enhanced ability to oxidize fat during exercise across a range of intensities is striking, as is the ability to maintain “normal” glycogen concentrations in the context of limited carbohydrate intake. Keto-adaptation provides an alternative to the supremacy of the high-carbohydrate paradigm for endurance athletes.

https://www.metabolismjournal.com/article/S0026-0495(15)00334-0/fulltext

Nutritional Ketosis Alters Fuel Preference and Thereby Endurance Performance in Athletes

Détails

Catégorie : Ketogenic Diet / Healthy diet

Publication : mardi 29 juin 2021 06:31

"We have demonstrated the metabolic effects of elevated circulating ketone bodies as a fuel and biological signal to create a unique physiological condition. Ketosis may alter substrate competition for respiration, while improving oxidative energy transduction under certain conditions, such as endurance exer-cise. Consequently, nutritional ketosis may help to unlock greater human metabolic potential."

https://www.cell.com/cell-metabolism/pdfExtended/S1550-4131(16)30355-2 

Nutritional Ketosis Increases NAD+/NADH Ratio in Healthy Human Brain: An in Vivo Study by 31P-MRS

Détails

Catégorie : Ketogenic Diet / Healthy diet

Publication : mardi 29 juin 2021 06:02

"The NAD⁺ requirement of the glycolytic and ketolytic pathways is illustrated in Figure 3. Glycolysis requires 4 NAD⁺ to make 2 Acetyl-CoA, while ketolysis consumes no NAD⁺ to make Acetyl-CoA from AcA, and only one NAD⁺ to convert BHB to AcA (6). This is to the best of our knowledge the first interventional study that shows that ketones can have a NAD⁺ sparing effect in healthy human brain."

https://www.frontiersin.org/articles/10.3389/fnut.2018.00062/full

Notable Limitation: funded by Nestlé.